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HIV Target gene Detail Information

> SF1 Gene Search Result


Gene Information
Gene Name SF1
Gene ID 7536
Gene Full Name splicing factor 1
Gene Alias BBP; MBBP; ZFM1; ZNF162; D11S636; ZCCHC25
Transcripts ENSG00000168066
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q15637
HGNC ID HGNC:12950
VEGA ID OTTHUMG00000066833
OMIM ID 601516
String ID 9606.ENSP00000366604
Drugbank ID BE0009043
PharmGKB ID PA37533
Target gene [SF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000548 chr11 338 24 17 379 View
4000685 chr11 220 63 36 319 View
4001581 chr11 145 4 149 View
4002569 chr11 63 26 89 View
4002628 chr11 83 3 86 View
4002769 chr17 78 3 81 View
4002796 chr11 79 79 View
4002845 chr8 70 2 5 77 View
4002846 chr8 70 2 5 77 View
4002990 chr17 71 2 73 View
4003490 chr12 60 60 View
4003982 chr8 45 4 2 51 View
4004216 chr11 47 47 View
4005185 chr11 33 2 35 View
4005261 chr11 34 34 View
4005415 chr11 33 33 View
4006630 chr12 16 6 1 23 View
4007309 chr11 14 6 20 View
4013375 chr8 3 3 View
4016107 chr8 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SF1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SF1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).