HIV Target gene Detail Information

> SEZ6L2 Gene Search Result

Gene Information

Gene Name	SEZ6L2
Gene ID	26470
Gene Full Name	seizure related 6 homolog like 2
Gene Alias	BSRPA; PSK-1
Transcripts	ENSG00000174938
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6UXD5
HGNC ID	HGNC:30844
VEGA ID	OTTHUMG00000132112
OMIM ID	616667
String ID	9606.ENSP00000481917
PharmGKB ID	PA134924025

Target gene [SEZ6L2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004528	chr16	43			43	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SEZ6L2 expression and immune infiltrating cell level correlation result in HIV+ samples
SEZ6L2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).