HIV Target gene Detail Information

> SET Gene Search Result

Gene Information

Gene Name	SET
Gene ID	6418
Gene Full Name	SET nuclear proto-oncogene
Gene Alias	2PP2A; IGAAD; MRD58; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA
Transcripts	ENSG00000119335
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Lipid droplets;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q01105
HGNC ID	HGNC:10760
VEGA ID	OTTHUMG00000020755
OMIM ID	600960
String ID	9606.ENSP00000361777
PharmGKB ID	PA35678

Target gene [SET] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001123	chr9	203	7		210	View
4001178	chr9	194	6		200	View
4001476	chr9	154	5		159	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SET expression and immune infiltrating cell level correlation result in HIV+ samples
SET expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SET expression and immune infiltrating cell level correlation result in HIV+ samples
SET expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).