HBV Target gene Detail Information

> SERPINF2 Gene Search Result


Gene Information
Gene Name SERPINF2
Gene ID 5345
Gene Full Name serpin family F member 2
Gene Alias AAP; API; PLI; A2AP; ALPHA-2-PI
Transcripts ENSG00000276838
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID P08697
HGNC ID HGNC:9075
VEGA ID OTTHUMG00000191167
OMIM ID 613168
String ID 9606.ENSP00000321853
Drugbank ID BE0001125
PharmGKB ID PA35522
Target gene [SERPINF2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002773 chr17 91 68 48 207 View
1003958 chr17 19 81 100 View
1012982 chr17 1 5 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SERPINF2 expression and immune infiltrating cell level correlation result in HBV+ samples
SERPINF2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).