HBV Target gene Detail Information

> SERPINF1 Gene Search Result


Gene Information
Gene Name SERPINF1
Gene ID 5176
Gene Full Name serpin family F member 1
Gene Alias OI6; OI12; PEDF; EPC-1; PIG35
Transcripts ENSG00000282307
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P36955
HGNC ID HGNC:8824
VEGA ID OTTHUMG00000191168
OMIM ID 172860
String ID 9606.ENSP00000254722
Drugbank ID BE0008993
PharmGKB ID PA35508
Target gene [SERPINF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001441 chr17 625 52 30 707 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SERPINF1 expression and immune infiltrating cell level correlation result in HBV+ samples
SERPINF1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).