HIV Target gene Detail Information

> SERPINB7 Gene Search Result

Gene Information

Gene Name	SERPINB7
Gene ID	8710
Gene Full Name	serpin family B member 7
Gene Alias	PPKN; TP55; MEGSIN
Transcripts	ENSG00000166396
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Mitochondria;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O75635
HGNC ID	HGNC:13902
VEGA ID	OTTHUMG00000060591
OMIM ID	603357
String ID	9606.ENSP00000381101
PharmGKB ID	PA37825

Target gene [SERPINB7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003655	chr18	55		2	57	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SERPINB7 expression and immune infiltrating cell level correlation result in HIV+ samples
SERPINB7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).