HIV Target gene Detail Information

> SERINC5 Gene Search Result

Gene Information

Gene Name	SERINC5
Gene ID	256987
Gene Full Name	serine incorporator 5
Gene Alias	TPO1; C5orf12
Transcripts	ENSG00000164300
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Centrosome;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q86VE9
HGNC ID	HGNC:18825
VEGA ID	OTTHUMG00000162563
OMIM ID	614551
String ID	9606.ENSP00000426237
PharmGKB ID	PA38698

Target gene [SERINC5] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	33800773	N51T	Nef	C	View
2	33800773	H116N	Nef	C	View
3	33800773	V148L	Nef	C	View
4	33800773	V148X	Nef	C	View
5	33800773	M168I	Nef	C	View
6	33800773	M168X	Nef	C	View
7	33800773	R178G	Nef	C	View
8	33800773	S163C	Nef	C	View
9	33800773	I114V	Nef	C	View

Target gene [SERINC5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000012	chr5	707	1294	1107	3108	View
4001154	chr5	201	3		204	View
4002098	chr5	62	17	33	112	View
4002986	chr5	27	31	15	73	View
4008556	chr5	13	1	1	15	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).