Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Target gene Detail Information

> SERINC3 Gene Search Result


Gene Information
Gene Name SERINC3
Gene ID 10955
Gene Full Name serine incorporator 3
Gene Alias TDE; TDE1; AIGP1; TMS-1; DIFF33; SBBI99
Transcripts ENSG00000132824
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID Q13530
HGNC ID HGNC:11699
VEGA ID OTTHUMG00000033087
OMIM ID 607165
String ID 9606.ENSP00000340243
PharmGKB ID PA36418
Target gene [SERINC3] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 33800773 N51T
Nef
C
 View
2 33800773 H116N
Nef
C
 View
3 33800773 V148L
Nef
C
 View
4 33800773 V148X
Nef
C
 View
5 33800773 M168I
Nef
C
 View
6 33800773 M168X
Nef
C
 View
7 33800773 R178G
Nef
C
 View
8 33800773 S163C
Nef
C
 View
9 33800773 I114V
Nef
C
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SERINC3 expression and immune infiltrating cell level correlation result in HIV+ samples
SERINC3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SERINC3 expression and immune infiltrating cell level correlation result in HIV+ samples
SERINC3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).