HBV Target gene Detail Information

> SERBP1 Gene Search Result

Gene Information

Gene Name	SERBP1
Gene ID	26135
Gene Full Name	SERPINE1 mRNA binding protein 1
Gene Alias	CGI-55; CHD3IP; HABP4L; PAIRBP1; PAI-RBP1
Transcripts	ENSG00000142864
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8NC51
HGNC ID	HGNC:17860
VEGA ID	OTTHUMG00000009372
OMIM ID	607378
String ID	9606.ENSP00000360034
PharmGKB ID	PA413

Target gene [SERBP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000422	chr1	2123	201	47	2371	View
1004766	chr1	56	14		70	View
1008432	chr1	16	5		21	View
1008444	chr1	16	5		21	View
1013333	chr1	5			5	View
1013993	chr1	4			4	View
1404369	chr1	39	10		49	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of SERBP1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SERBP1 expression: Low -> High
Lollipop of SERBP1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of SERBP1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SERBP1 expression and immune infiltrating cell level correlation result in HBV+ samples
SERBP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).