HBV Target gene Detail Information

> SEMA6B Gene Search Result

Gene Information

Gene Name	SEMA6B
Gene ID	10501
Gene Full Name	semaphorin 6B
Gene Alias	SEMAN; semaZ; SEMA-VIB; SEM-SEMA-Y
Transcripts	ENSG00000167680
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins
Uniport_ID	Q9H3T3
HGNC ID	HGNC:10739
VEGA ID	OTTHUMG00000182011
OMIM ID	608873
String ID	9606.ENSP00000467290
PharmGKB ID	PA35661

Target gene [SEMA6B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002861	chr19	143	50	1	194	View
1002869	chr19	143	49	1	193	View
1002870	chr19	143	49	1	193	View
1005081	chr19	53	7	1	61	View
1010640	chr19	10	1		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SEMA6B expression and immune infiltrating cell level correlation result in HBV+ samples
SEMA6B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).