HBV Target gene Detail Information

> SEMA5A Gene Search Result

Gene Information

Gene Name	SEMA5A
Gene ID	9037
Gene Full Name	semaphorin 5A
Gene Alias	semF; SEMAF
Transcripts	ENSG00000112902
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q13591
HGNC ID	HGNC:10736
VEGA ID	OTTHUMG00000090501
OMIM ID	609297
String ID	9606.ENSP00000371936
PharmGKB ID	PA35658

Target gene [SEMA5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004155	chr5	85	5	1	91	View
1005905	chr5	46			46	View
1007288	chr5	27		1	28	View
1007541	chr5	25		1	26	View
1008032	chr5	15	8		23	View
1018421	chr5				0	View
1400142	chr5				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SEMA5A expression and immune infiltrating cell level correlation result in HBV+ samples
SEMA5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).