HBV Target gene Detail Information

> SEMA3D Gene Search Result

Gene Information

Gene Name	SEMA3D
Gene ID	223117
Gene Full Name	semaphorin 3D
Gene Alias	coll-2; Sema-Z2
Transcripts	ENSG00000153993
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Plasma membrane;Predicted to be secreted;
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	O95025
HGNC ID	HGNC:10726
VEGA ID	OTTHUMG00000154569
OMIM ID	609907
String ID	9606.ENSP00000284136
PharmGKB ID	PA35648

Target gene [SEMA3D] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016614	chr7	1			1	View
1016615	chr7	1			1	View
1016616	chr7	1			1	View
1404219	chr7	26	12		38	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SEMA3D expression and immune infiltrating cell level correlation result in HBV+ samples
SEMA3D expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).