HBV Target gene Detail Information

> SEL1L3 Gene Search Result


Gene Information
Gene Name SEL1L3
Gene ID 23231
Gene Full Name SEL1L family member 3
Gene Alias Sel-1L3
Transcripts ENSG00000091490
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q68CR1
HGNC ID HGNC:29108
VEGA ID OTTHUMG00000160331
String ID 9606.ENSP00000382767
PharmGKB ID PA165664479
Target gene [SEL1L3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007279 chr4 22 6 28 View
1401456 chr4 22 6 28 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SEL1L3 expression and immune infiltrating cell level correlation result in HBV+ samples
SEL1L3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).