HIV Target gene Detail Information

> SEL1L Gene Search Result

Gene Information

Gene Name	SEL1L
Gene ID	6400
Gene Full Name	SEL1L, ERAD E3 ligase adaptor subunit
Gene Alias	SEL1L1; PRO1063; SEL1-LIKE
Transcripts	ENSG00000071537
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9UBV2
HGNC ID	HGNC:10717
VEGA ID	OTTHUMG00000171419
OMIM ID	602329
String ID	9606.ENSP00000337053
PharmGKB ID	PA35639

Target gene [SEL1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000531	chr14	306	20	69	395	View
4003111	chr14	36	20	13	69	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SEL1L expression and immune infiltrating cell level correlation result in HIV+ samples
SEL1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SEL1L expression and immune infiltrating cell level correlation result in HIV+ samples
SEL1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).