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HBV Target gene Detail Information

> SEH1L Gene Search Result


Gene Information
Gene Name SEH1L
Gene ID 81929
Gene Full Name SEH1 like nucleoporin
Gene Alias Seh1; SEH1A; SEH1B; SEC13L
Transcripts ENSG00000085415
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transporters
Uniport_ID Q96EE3
HGNC ID HGNC:30379
VEGA ID OTTHUMG00000181909
OMIM ID 609263
String ID 9606.ENSP00000382779
PharmGKB ID PA134912135
Target gene [SEH1L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1402912 chr18 2508 259 113 2880 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SEH1L expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SEH1L expression: Low -> High
Lollipop of SEH1L expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SEH1L expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SEH1L expression and immune infiltrating cell level correlation result in HBV+ samples
SEH1L expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).