HIV Target gene Detail Information

> SECISBP2 Gene Search Result

Gene Information

Gene Name	SECISBP2
Gene ID	79048
Gene Full Name	SECIS binding protein 2
Gene Alias	SBP2
Transcripts	ENSG00000187742
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q96T21
HGNC ID	HGNC:30972
VEGA ID	OTTHUMG00000020182
OMIM ID	607693
String ID	9606.ENSP00000364965
PharmGKB ID	PA134863749

Target gene [SECISBP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001101	chr9	155	46	14	215	View
4001292	chr9	133	33	16	182	View
4001539	chr9	99	44	10	153	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SECISBP2 expression and immune infiltrating cell level correlation result in HIV+ samples
SECISBP2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SECISBP2 expression and immune infiltrating cell level correlation result in HIV+ samples
SECISBP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).