HIV Target gene Detail Information

> SEC31A Gene Search Result

Gene Information

Gene Name	SEC31A
Gene ID	22872
Gene Full Name	SEC31 homolog A, COPII coat complex component
Gene Alias	ABP125; ABP130; HSPC275; HSPC334; SEC31L1
Transcripts	ENSG00000138674
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O94979
HGNC ID	HGNC:17052
VEGA ID	OTTHUMG00000130297
OMIM ID	610257
String ID	9606.ENSP00000378721
PharmGKB ID	PA162402737

Target gene [SEC31A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010063	chr4	9	1		10	View
4014475	chr4	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SEC31A expression and immune infiltrating cell level correlation result in HIV+ samples
SEC31A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SEC31A expression and immune infiltrating cell level correlation result in HIV+ samples
SEC31A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).