HIV Target gene Detail Information

> SEC24C Gene Search Result

Gene Information

Gene Name	SEC24C
Gene ID	9632
Gene Full Name	SEC24 homolog C, COPII coat complex component
Transcripts	ENSG00000176986
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P53992
HGNC ID	HGNC:10705
VEGA ID	OTTHUMG00000018476
OMIM ID	607185
String ID	9606.ENSP00000343405
PharmGKB ID	PA35628

Target gene [SEC24C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008753	chr10	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SEC24C expression and immune infiltrating cell level correlation result in HIV+ samples
SEC24C expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SEC24C expression and immune infiltrating cell level correlation result in HIV+ samples
SEC24C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).