HIV Target gene Detail Information

> SEC24B Gene Search Result


Gene Information
Gene Name SEC24B
Gene ID 10427
Gene Full Name SEC24 homolog B, COPII coat complex component
Gene Alias SEC24
Transcripts ENSG00000138802
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O95487
HGNC ID HGNC:10704
VEGA ID OTTHUMG00000161372
OMIM ID 607184
String ID 9606.ENSP00000428564
PharmGKB ID PA35627
Target gene [SEC24B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006891 chr4 18 4 22 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SEC24B expression and immune infiltrating cell level correlation result in HIV+ samples
SEC24B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SEC24B expression and immune infiltrating cell level correlation result in HIV+ samples
SEC24B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).