HIV Target gene Detail Information

> SEC23A Gene Search Result

Gene Information

Gene Name	SEC23A
Gene ID	10484
Gene Full Name	Sec23 homolog A, coat complex II component
Gene Alias	CLSD; hSec23A
Transcripts	ENSG00000100934
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q15436
HGNC ID	HGNC:10701
VEGA ID	OTTHUMG00000028812
OMIM ID	610511
String ID	9606.ENSP00000306881
PharmGKB ID	PA35624

Target gene [SEC23A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008144	chr14	13	3		16	View
4011128	chr14		7		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SEC23A expression and immune infiltrating cell level correlation result in HIV+ samples
SEC23A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SEC23A expression and immune infiltrating cell level correlation result in HIV+ samples
SEC23A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).