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HTLV1 Target gene Detail Information

> SEC22A Gene Search Result


Gene Information
Gene Name SEC22A
Gene ID 26984
Gene Full Name SEC22 homolog A, vesicle trafficking protein
Gene Alias SEC22L2
Transcripts ENSG00000121542
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q96IW7
HGNC ID HGNC:20260
VEGA ID OTTHUMG00000159495
OMIM ID 612442
String ID 9606.ENSP00000310521
PharmGKB ID PA134921956
Target gene [SEC22A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008066 chr3 45 4 49 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SEC22A expression and immune infiltrating cell level correlation result in HTLV1+ samples
SEC22A expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SEC22A expression and immune infiltrating cell level correlation result in HTLV1+ samples
SEC22A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).