HIV Target gene Detail Information

> SEC16A Gene Search Result

Gene Information

Gene Name	SEC16A
Gene ID	9919
Gene Full Name	SEC16 homolog A, endoplasmic reticulum export factor
Gene Alias	p250; SEC16L; KIAA0310
Transcripts	ENSG00000148396
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Endoplasmic reticulum;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O15027
HGNC ID	HGNC:29006
VEGA ID	OTTHUMG00000020932
OMIM ID	612854
String ID	9606.ENSP00000325827
PharmGKB ID	PA162402611

Target gene [SEC16A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002157	chr9	107	2		109	View
4002727	chr9	65	17		82	View
4004111	chr9	11	30	8	49	View
4004813	chr9	12	25	2	39	View
4005465	chr9	31	1		32	View
4006014	chr9	14	14		28	View
4006551	chr9	3	9	12	24	View
4008859	chr9	10	3		13	View
4011342	chr9	3	2	2	7	View
4012617	chr9	4			4	View
4013755	chr9	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SEC16A expression and immune infiltrating cell level correlation result in HIV+ samples
SEC16A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SEC16A expression and immune infiltrating cell level correlation result in HIV+ samples
SEC16A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).