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HIV Target gene Detail Information

> SDHC Gene Search Result


Gene Information
Gene Name SDHC
Gene ID 6391
Gene Full Name succinate dehydrogenase complex subunit C
Gene Alias CYBL; PGL3; QPS1; SDH3; CYB560
Transcripts ENSG00000143252
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q99643
HGNC ID HGNC:10682
VEGA ID OTTHUMG00000034468
OMIM ID 602413
String ID 9606.ENSP00000356953
Drugbank ID BE0002257; BE0003846
PharmGKB ID PA35607
Target gene [SDHC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006176 chr1 22 1 3 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SDHC expression and immune infiltrating cell level correlation result in HIV+ samples
SDHC expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SDHC expression and immune infiltrating cell level correlation result in HIV+ samples
SDHC expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).