HBV Target gene Detail Information

> SCTR Gene Search Result

Gene Information

Gene Name	SCTR
Gene ID	6344
Gene Full Name	secretin receptor
Gene Alias	SR
Transcripts	ENSG00000080293
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID	P47872
HGNC ID	HGNC:10608
VEGA ID	OTTHUMG00000131407
OMIM ID	182098
String ID	9606.ENSP00000019103
Drugbank ID	BE0000318
PharmGKB ID	PA35018

Target gene [SCTR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005067	chr2	61	1		62	View
1400504	chr2	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SCTR expression and immune infiltrating cell level correlation result in HBV+ samples
SCTR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).