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EBV Target gene Detail Information

> SCN7A Gene Search Result


Gene Information
Gene Name SCN7A
Gene ID 6332
Gene Full Name sodium voltage-gated channel alpha subunit 7
Gene Alias NaG; SCN6A; Nav2.1; Nav2.2
Transcripts ENSG00000136546
Virus EBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, Plasma proteins, Predicted membrane proteins
Uniport_ID Q01118
HGNC ID HGNC:10594
VEGA ID OTTHUMG00000154078
OMIM ID 182392
String ID 9606.ENSP00000386796
Drugbank ID BE0004833; BE0009738; BE0004901
PharmGKB ID PA35008
Target gene [SCN7A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000381 chr2 9 12 4 25 View
3001059 chr2 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of SCN7A expression and immune infiltrating cell level correlation result in EBV+ samples
SCN7A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).