HBV Target gene Detail Information

> SCN3B Gene Search Result

Gene Information

Gene Name	SCN3B
Gene ID	55800
Gene Full Name	sodium voltage-gated channel beta subunit 3
Gene Alias	SCNB3; ATFB16; BRGDA7; HSA243396
Transcripts	ENSG00000166257
Virus	HBV
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9NY72
HGNC ID	HGNC:20665
VEGA ID	OTTHUMG00000166006
OMIM ID	608214
String ID	9606.ENSP00000376523
Drugbank ID	BE0003637; BE0004901
PharmGKB ID	PA130546912

Target gene [SCN3B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016139	chr11	1	1		2	View
1017477	chr11	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SCN3B expression and immune infiltrating cell level correlation result in HBV+ samples
SCN3B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).