HBV Target gene Detail Information

> SCN11A Gene Search Result

Gene Information

Gene Name	SCN11A
Gene ID	11280
Gene Full Name	sodium voltage-gated channel alpha subunit 11
Gene Alias	NaN; PN5; FEPS3; HSAN7; SNS-2; NAV1.9; SCN12A
Transcripts	ENSG00000168356
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	Q9UI33
HGNC ID	HGNC:10583
VEGA ID	OTTHUMG00000048246
OMIM ID	604385
String ID	9606.ENSP00000307599
Drugbank ID	BE0000192; BE0009738; BE0004901
PharmGKB ID	PA35001

Target gene [SCN11A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009929	chr3	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SCN11A expression and immune infiltrating cell level correlation result in HBV+ samples
SCN11A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).