HIV Target gene Detail Information

> SCD Gene Search Result


Gene Information
Gene Name SCD
Gene ID 6319
Gene Full Name stearoyl-CoA desaturase
Gene Alias SCD1; FADS5; SCDOS; hSCD1; MSTP008
Transcripts ENSG00000099194
Virus HIV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Uniport_ID O00767
HGNC ID HGNC:10571
VEGA ID OTTHUMG00000018906
OMIM ID 604031
String ID 9606.ENSP00000359380
PharmGKB ID PA34984
Target gene [SCD] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4009892 chr10 2 8 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SCD expression and immune infiltrating cell level correlation result in HIV+ samples
SCD expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SCD expression and immune infiltrating cell level correlation result in HIV+ samples
SCD expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).