HBV Target gene Detail Information

> SCARB1 Gene Search Result

Gene Information

Gene Name	SCARB1
Gene ID	949
Gene Full Name	scavenger receptor class B member 1
Gene Alias	CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6
Transcripts	ENSG00000073060
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Lysosomes;Rods & Rings;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q8WTV0
HGNC ID	HGNC:1664
VEGA ID	OTTHUMG00000168544
OMIM ID	601040
String ID	9606.ENSP00000261693
Drugbank ID	BE0000189
PharmGKB ID	PA97

Target gene [SCARB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008694	chr12	8	11		19	View
1400506	chr12	15	4		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SCARB1 expression and immune infiltrating cell level correlation result in HBV+ samples
SCARB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).