HIV Target gene Detail Information

> SCAP Gene Search Result

Gene Information

Gene Name	SCAP
Gene ID	22937
Gene Full Name	SREBF chaperone
Transcripts	ENSG00000114650
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q12770
HGNC ID	HGNC:30634
VEGA ID	OTTHUMG00000125539
OMIM ID	601510
String ID	9606.ENSP00000265565
PharmGKB ID	PA162402461

Target gene [SCAP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001094	chr3	89	99	28	216	View
4007370	chr3	18		1	19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SCAP expression and immune infiltrating cell level correlation result in HIV+ samples
SCAP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SCAP expression and immune infiltrating cell level correlation result in HIV+ samples
SCAP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).