HIV Target gene Detail Information

> SBF1 Gene Search Result

Gene Information

Gene Name	SBF1
Gene ID	6305
Gene Full Name	SET binding factor 1
Gene Alias	MTMR5; CMT4B3; DENND7A
Transcripts	ENSG00000100241
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O95248
HGNC ID	HGNC:10542
VEGA ID	OTTHUMG00000150204
OMIM ID	603560
String ID	9606.ENSP00000370196
PharmGKB ID	PA34953

Target gene [SBF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003636	chr22	10	36	11	57	View
4010428	chr22	4	5		9	View
4015106	chr22		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SBF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SBF1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SBF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SBF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).