Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> SAR1A Gene Search Result


Gene Information
Gene Name SAR1A
Gene ID 56681
Gene Full Name secretion associated Ras related GTPase 1A
Gene Alias SAR1; Sara; SARA1; masra2
Transcripts ENSG00000079332
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9NR31
HGNC ID HGNC:10534
VEGA ID OTTHUMG00000018400
OMIM ID 607691
String ID 9606.ENSP00000362339
PharmGKB ID PA34942
Target gene [SAR1A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002538 chr10 222 13 17 252 View
1401527 chr10 222 13 17 252 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SAR1A expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SAR1A expression: Low -> High
Lollipop of SAR1A expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SAR1A expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SAR1A expression and immune infiltrating cell level correlation result in HBV+ samples
SAR1A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).