HIV Target gene Detail Information

> SAMSN1 Gene Search Result

Gene Information

Gene Name	SAMSN1
Gene ID	64092
Gene Alias	SLy2; HACS1; NASH1; SASH2; SH3D6B
Transcripts	ENSG00000155307
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NSI8
HGNC ID	HGNC:10528
VEGA ID	OTTHUMG00000074317
OMIM ID	607978
String ID	9606.ENSP00000285670
PharmGKB ID	PA34939

Target gene [SAMSN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001060	chr21	198	25		223	View
4001070	chr21	164	32	31	227	View
4003104	chr21	3	58	8	69	View
4003980	chr21	12	38	1	51	View
4005173	chr21	21	5	9	35	View
4013674	chr21	2	1		3	View
4014089	chr21	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SAMSN1 expression and immune infiltrating cell level correlation result in HIV+ samples
SAMSN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SAMSN1 expression and immune infiltrating cell level correlation result in HIV+ samples
SAMSN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).