HIV Target gene Detail Information

> SAMM50 Gene Search Result

Gene Information

Gene Name	SAMM50
Gene ID	25813
Gene Full Name	SAMM50 sorting and assembly machinery component
Gene Alias	OMP85; SAM50; TOB55; TRG-3; CGI-51; YNL026W
Transcripts	ENSG00000100347
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins, Transporters
Uniport_ID	Q9Y512
HGNC ID	HGNC:24276
VEGA ID	OTTHUMG00000150557
OMIM ID	612058
String ID	9606.ENSP00000345445
PharmGKB ID	PA142670954

Target gene [SAMM50] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001850	chr22	78	44	5	127	View
4012305	chr22	1	4		5	View
4012756	chr22	1	3		4	View
4014629	chr22	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SAMM50 expression and immune infiltrating cell level correlation result in HIV+ samples
SAMM50 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SAMM50 expression and immune infiltrating cell level correlation result in HIV+ samples
SAMM50 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).