HIV Target gene Detail Information

> SAMHD1 Gene Search Result

Gene Information

Gene Name	SAMHD1
Gene ID	25939
Gene Full Name	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Gene Alias	DCIP; CHBL2; HDDC1; MOP-5; SBBI88; hSAMHD1
Transcripts	ENSG00000101347
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y3Z3
HGNC ID	HGNC:15925
VEGA ID	OTTHUMG00000032402
OMIM ID	606754
String ID	9606.ENSP00000262878
PharmGKB ID	PA34938

Target gene [SAMHD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002732	chr20	33	10	39	82	View
4005460	chr20	28	4		32	View
4005983	chr20	26	2		28	View
4006340	chr20	9	5	11	25	View
4010420	chr20	8	1		9	View
4013197	chr20	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SAMHD1 expression and immune infiltrating cell level correlation result in HIV+ samples
SAMHD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).