EBV Target gene Detail Information

> S100B Gene Search Result


Gene Information
Gene Name S100B
Gene ID 6285
Gene Full Name S100 calcium binding protein B
Gene Alias NEF; S100; S100-B; S100beta
Transcripts ENSG00000160307
Virus EBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters
Uniport_ID P04271
HGNC ID HGNC:10500
VEGA ID OTTHUMG00000090715
OMIM ID 176990
String ID 9606.ENSP00000291700
Drugbank ID BE0001177
PharmGKB ID PA34912
Target gene [S100B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000053 chr21 68 151 286 505 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of S100B expression and immune infiltrating cell level correlation result in EBV+ samples
S100B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).