HIV Target gene Detail Information

> RYK Gene Search Result

Gene Information

Gene Name	RYK
Gene ID	6259
Gene Full Name	receptor-like tyrosine kinase
Gene Alias	JTK5; RYK1; JTK5A; D3S3195
Transcripts	ENSG00000163785
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
HGNC ID	HGNC:10481
VEGA ID	OTTHUMG00000159750
OMIM ID	600524
String ID	9606.ENSP00000478721
PharmGKB ID	PA34894

Target gene [RYK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004308	chr3	46			46	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RYK expression and immune infiltrating cell level correlation result in HIV+ samples
RYK expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RYK expression and immune infiltrating cell level correlation result in HIV+ samples
RYK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).