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HBV Target gene Detail Information

> RYBP Gene Search Result


Gene Information
Gene Name RYBP
Gene ID 23429
Gene Full Name RING1 and YY1 binding protein
Gene Alias AAP1; DEDAF; YEAF1; APAP-1
Transcripts ENSG00000281766
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N488
HGNC ID HGNC:10480
VEGA ID OTTHUMG00000159190
OMIM ID 607535
String ID 9606.ENSP00000419494
PharmGKB ID PA34893
Target gene [RYBP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005845 chr3 24 23 47 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RYBP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RYBP expression: Low -> High
Lollipop of RYBP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RYBP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RYBP expression and immune infiltrating cell level correlation result in HBV+ samples
RYBP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).