HBV Target gene Detail Information

> RXFP2 Gene Search Result

Gene Information

Gene Name	RXFP2
Gene ID	122042
Gene Full Name	relaxin family peptide receptor 2
Gene Alias	LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2
Transcripts	ENSG00000133105
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q8WXD0
HGNC ID	HGNC:17318
VEGA ID	OTTHUMG00000016690
OMIM ID	606655
String ID	9606.ENSP00000298386
PharmGKB ID	PA134918556

Target gene [RXFP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003304	chr13	26	96	24	146	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RXFP2 expression and immune infiltrating cell level correlation result in HBV+ samples
RXFP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).