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HBV Target gene Detail Information

> RTN3 Gene Search Result


Gene Information
Gene Name RTN3
Gene ID 10313
Gene Full Name reticulon 3
Gene Alias HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
Transcripts ENSG00000133318
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O95197
HGNC ID HGNC:10469
VEGA ID OTTHUMG00000168056
OMIM ID 604249
String ID 9606.ENSP00000367050
PharmGKB ID PA34882
Target gene [RTN3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004824 chr11 25 41 2 68 View
1006527 chr11 16 21 37 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RTN3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RTN3 expression: Low -> High
Lollipop of RTN3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RTN3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RTN3 expression and immune infiltrating cell level correlation result in HBV+ samples
RTN3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).