HIV Target gene Detail Information

> RTCB Gene Search Result

Gene Information

Gene Name	RTCB
Gene ID	51493
Gene Full Name	RNA 2',3'-cyclic phosphate and 5'-OH ligase
Gene Alias	FAAP; HSPC117; C22orf28; DJ149A16.6
Transcripts	ENSG00000100220
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Vesicles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9Y3I0
HGNC ID	HGNC:26935
VEGA ID	OTTHUMG00000030300
OMIM ID	613901
String ID	9606.ENSP00000216038
Drugbank ID	BE0004442
PharmGKB ID	PA145149387

Target gene [RTCB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006698	chr22	23			23	View
4009956	chr22	9	1		10	View
4012111	chr22	3	2		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RTCB expression and immune infiltrating cell level correlation result in HIV+ samples
RTCB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).