HIV Target gene Detail Information

> RSRC2 Gene Search Result

Gene Information

Gene Name	RSRC2
Gene ID	65117
Gene Full Name	arginine and serine rich coiled-coil 2
Transcripts	ENSG00000111011
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;Nucleoli fibrillar center;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q7L4I2
HGNC ID	HGNC:30559
VEGA ID	OTTHUMG00000167572
String ID	9606.ENSP00000330188
PharmGKB ID	PA162402249

Target gene [RSRC2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003130	chr12	20	48	1	69	View
4003131	chr12	20	48	1	69	View
4003132	chr12	20	48	1	69	View
4003371	chr12	20	42	1	63	View
4003617	chr12	20	37	1	58	View
4004126	chr12	44	4	1	49	View
4005482	chr12	31	1		32	View
4006914	chr12	22			22	View
4011564	chr12	5	1		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RSRC2 expression and immune infiltrating cell level correlation result in HIV+ samples
RSRC2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RSRC2 expression and immune infiltrating cell level correlation result in HIV+ samples
RSRC2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).