HIV Target gene Detail Information

> RSBN1 Gene Search Result

Gene Information

Gene Name	RSBN1
Gene ID	54665
Gene Full Name	round spermatid basic protein 1
Gene Alias	KDM9; ROSBIN
Transcripts	ENSG00000081019
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5VWQ0
HGNC ID	HGNC:25642
VEGA ID	OTTHUMG00000011938
OMIM ID	615858
String ID	9606.ENSP00000261441
PharmGKB ID	PA134869532

Target gene [RSBN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000333	chr1	231	174	124	529	View
4000514	chr1	321	66	20	407	View
4004487	chr1	42	1		43	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RSBN1 expression and immune infiltrating cell level correlation result in HIV+ samples
RSBN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RSBN1 expression and immune infiltrating cell level correlation result in HIV+ samples
RSBN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).