HIV Target gene Detail Information

> RRAS2 Gene Search Result

Gene Information

Gene Name	RRAS2
Gene ID	22800
Gene Full Name	RAS related 2
Gene Alias	TC21
Transcripts	ENSG00000133818
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, RAS pathway related proteins
Gene Function	Oncogene
Uniport_ID	P62070
HGNC ID	HGNC:17271
VEGA ID	OTTHUMG00000165756
OMIM ID	600098
String ID	9606.ENSP00000256196
PharmGKB ID	PA34862

Target gene [RRAS2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008391	chr11	9	6		15	View
4014330	chr11	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RRAS2 expression and immune infiltrating cell level correlation result in HIV+ samples
RRAS2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RRAS2 expression and immune infiltrating cell level correlation result in HIV+ samples
RRAS2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).