HIV Target gene Detail Information

> RPS6KA6 Gene Search Result

Gene Information

Gene Name	RPS6KA6
Gene ID	27330
Gene Full Name	ribosomal protein S6 kinase A6
Gene Alias	RSK4; RSK-4; p90RSK6; PP90RSK4; S6K-alpha-6
Transcripts	ENSG00000072133
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;Nucleoli;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9UK32
HGNC ID	HGNC:10435
VEGA ID	OTTHUMG00000021923
OMIM ID	300303
String ID	9606.ENSP00000262752
Drugbank ID	BE0009334
PharmGKB ID	PA34850

Target gene [RPS6KA6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011642	chrX		6		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RPS6KA6 expression and immune infiltrating cell level correlation result in HIV+ samples
RPS6KA6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).