HIV Target gene Detail Information

> RPS6KA4 Gene Search Result


Gene Information
Gene Name RPS6KA4
Gene ID 8986
Gene Full Name ribosomal protein S6 kinase A4
Gene Alias MSK2; RSK-B; S6K-alpha-4
Transcripts ENSG00000162302
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID O75676
HGNC ID HGNC:10433
VEGA ID OTTHUMG00000046094
OMIM ID 603606
String ID 9606.ENSP00000333896
Drugbank ID BE0004614
PharmGKB ID PA34848
Target gene [RPS6KA4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003658 chr11 19 15 23 57 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of RPS6KA4 expression and immune infiltrating cell level correlation result in HIV+ samples
RPS6KA4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of RPS6KA4 expression and immune infiltrating cell level correlation result in HIV+ samples
RPS6KA4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).