HBV Target gene Detail Information

> RPS28 Gene Search Result


Gene Information
Gene Name RPS28
Gene ID 6234
Gene Full Name ribosomal protein S28
Gene Alias S28; eS28; DBA15
Transcripts ENSG00000233927
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Ribosomal proteins
Uniport_ID P62857
HGNC ID HGNC:10418
VEGA ID OTTHUMG00000182460
OMIM ID 603685
String ID 9606.ENSP00000472469
Drugbank ID BE0009038
PharmGKB ID PA34825
Target gene [RPS28] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000184 chr19 3523 758 317 4598 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RPS28 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RPS28 expression: Low -> High
Lollipop of RPS28 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RPS28 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RPS28 expression and immune infiltrating cell level correlation result in HBV+ samples
RPS28 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).