HIV Target gene Detail Information

> RPS18 Gene Search Result

Gene Information

Gene Name	RPS18
Gene ID	6222
Gene Full Name	ribosomal protein S18
Gene Alias	KE3; S18; HKE3; KE-3; D6S218E
Transcripts	ENSG00000227794
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Ribosomal proteins
Uniport_ID	P62269
HGNC ID	HGNC:10401
VEGA ID	OTTHUMG00000012621
OMIM ID	180473
String ID	9606.ENSP00000393241
Drugbank ID	BE0009036
PharmGKB ID	PA34801

Target gene [RPS18] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001566	chr6	144	6		150	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RPS18 expression and immune infiltrating cell level correlation result in HIV+ samples
RPS18 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RPS18 expression and immune infiltrating cell level correlation result in HIV+ samples
RPS18 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).