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HIV Target gene Detail Information

> RPRD2 Gene Search Result


Gene Information
Gene Name RPRD2
Gene ID 23248
Gene Full Name regulation of nuclear pre-mRNA domain containing 2
Gene Alias HSPC099; KIAA0460
Transcripts ENSG00000163125
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5VT52
HGNC ID HGNC:29039
VEGA ID OTTHUMG00000012808
OMIM ID 614695
String ID 9606.ENSP00000358064
PharmGKB ID PA162402062
Target gene [RPRD2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001937 chr1 14 99 9 122 View
4002120 chr1 8 92 11 111 View
4007180 chr1 15 5 20 View
4009883 chr1 5 4 1 10 View
4010541 chr1 7 1 8 View
4011164 chr1 6 1 7 View
4016068 chr1 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of RPRD2 expression and immune infiltrating cell level correlation result in HIV+ samples
RPRD2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of RPRD2 expression and immune infiltrating cell level correlation result in HIV+ samples
RPRD2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).