HIV Target gene Detail Information

> RPRD1B Gene Search Result


Gene Information
Gene Name RPRD1B
Gene ID 58490
Gene Full Name regulation of nuclear pre-mRNA domain containing 1B
Gene Alias K-H; CREPT; NET60; C20orf77; Kub5-Hera; dJ1057B20.2
Transcripts ENSG00000101413
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NQG5
HGNC ID HGNC:16209
VEGA ID OTTHUMG00000032434
OMIM ID 614694
String ID 9606.ENSP00000362532
PharmGKB ID PA162402043
Target gene [RPRD1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001874 chr20 116 9 125 View
4007879 chr20 15 2 17 View
4010009 chr20 6 4 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of RPRD1B expression and immune infiltrating cell level correlation result in HIV+ samples
RPRD1B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of RPRD1B expression and immune infiltrating cell level correlation result in HIV+ samples
RPRD1B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).